Get Rid of MRSA — The Dermatologist's Guide

Common — Not Automatically Dangerous

MRSA is a group of bacteria — all staphs, all resistant to a specific family of antibiotics related to penicillin. In most cases it's found on people's skin without doing much of anything. Having MRSA on your skin is not automatically a medical emergency. But in specific individuals and circumstances, it can cause skin infections ranging from hypersensitivity and folliculitis to large abscesses and cellulitis — which can be very serious.

Recurring MRSA Is a Specific Problem

In some cases MRSA presents as a chronic or recurring issue — painful pimples appearing constantly or periodically. This happens when the bacteria continues to colonize reservoirs on the skin or on inanimate objects like fabric, and is never fully cleared. This requires a different approach than simply treating the active lesion.

See a Dermatologist First

MRSA is best managed with the help of a dermatologist. Many cases require tailored antibiotic selection based on the specific resistance and sensitivity of your strain — because each MRSA is different and will respond to different antibiotics. Response typically takes a few days to a few short weeks. A follow-up culture to confirm clearance is essential.

For Recurring MRSA: Decolonize

The reservoirs of MRSA on the body are the skin folds — behind the ears, under the nostrils, armpits, under the breasts, belly button, groin folds, and the buttock crease. These must be cleared by applying an antibiotic ointment targeting your specific MRSA strain — whether mupirocin, gentamicin, or triple-antibiotic ointment — twice daily for days to weeks until the MRSA is confirmed cleared.

Add an Antibacterial Wash

An antibacterial wash like chlorhexidine (Hibiclens) can further decrease MRSA numbers during the decolonization process. The combination of a leave-on antibiotic ointment plus an antibacterial wash works in the vast majority of cases — this dual approach is what keeps recurring infections away for good.

Launder Fabric in Hot Water and Bleach

During the decolonization process, launder all clothes and beddings in hot water with bleach. Inanimate objects like fabric can serve as reservoirs that reintroduce the bacteria to the skin, undermining treatment if not addressed simultaneously.

Consider Treating Household Members

In some cases, a family member — such as a spouse — can serve as an external reservoir and may need to be treated even if they are not showing signs of active MRSA infection. If MRSA keeps coming back despite full decolonization, this is worth exploring with your dermatologist.